| Identification | |
| Name: | Cilastatin |
| Synonyms: | Cilastatina;Cilastatine;Cilastatinum;MK-791;UNII-141A6AMN38;2-Heptenoic acid, 7-((2-amino-2-carboxyethyl)thio)-2-(((2,2-dimethylcyclopropyl)carbonyl)amino)-, (R-(R*,S*-(Z)))-;(Z)-7-[(2R)-2-amino-2-carboxyethyl]sulfanyl-2-[[(1S)-2,2-dimethylcyclopropanecarbonyl]amino]hept-2-enoic acid; |
| CAS: | 82009-34-5 |
| EINECS: | 279-875-8 |
| Molecular Formula: | C16H26N2O5S |
| Molecular Weight: | 358.45 |
| InChI: | InChI=1/C16H26N2O5S/c1-16(2)8-10(16)13(19)18-12(15(22)23)6-4-3-5-7-24-9-11(17)14(20)21/h6,10-11H,3-5,7-9,17H2,1-2H3,(H,18,19)(H,20,21)(H,22,23)/b12-6-/t10-,11+/m1/s1 |
| Molecular Structure: |  |
| Properties | |
| Density: | 1.275 g/cm3 |
| Refractive index: | 1.569 |
| Appearance: | White to light-yellow crystalline powder |
| Specification: |
?2-Heptenoic acid,7-[[(2R)-2-amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-,(2Z)- , with CAS number of 82009-34-5, can be called Cilastatin ; (z)-7-[(2s)-2-amino-3-hydroxy-3-oxopropyl]sulfanyl-2-[[(1s)-2,2-dimethylcyclopropanecarbonyl]amino]hept-2-enoic acid ; (r-(r*,s*-(z)))-)carbonyl)amino) ; mk-791;Cilastain ; (2Z)-7-[[(2R)-2-amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoic Acid ; Cilastatin acid ; (Z)-7-[(2S)-2-Amino-3-hydroxy-3-oxopropyl]sulfanyl-2-[[(1S)-2,2-dimethylcyclopropanecarbonyl]amino]hept-2-enoic acid . 2-Heptenoic acid,7-[[(2R)-2-amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-,(2Z)- (CAS NO.82009-34-5) is a white to light-yellow crystalline powder, it can prevent renal metabolism of penem and carbapenem antibiotics by specific and reversible dehydropeptidase, alsobe used as an antibacterial adjunct. |
| Usage: | Prevents renal metabolism of penem and carbapenem antibiotics by specific and reversible dehydropeptidase I inhibition. Antibacterial adjunct |
| Safety Data | |
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