| Identification |
| Name: | Nefazodone HCl |
| Synonyms: | Nefazodone hydrochloride;1-(3-(4-(m-Chlorophenyl)-1-piperazinyl)propyl)-3-ethyl-4-(2-phenoxyethyl)-delta(sup 2)-1,2,4-triazolin-5-one monohydrochloride;3H-1,2,4-Triazol-3-one, 2-(3-(4-(3-chlorophenyl)-1-piperazinyl))propyl)-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-, monohydrochloride;BMY 13754;Dutonin;Nefazodone;Reseril;Serzone; |
| CAS: | 82752-99-6 |
| Molecular Formula: | C25H33Cl2N5O2 |
| Molecular Weight: | 506.48 |
| InChI: | InChI=1/C25H32ClN5O2.ClH/c1-2-24-27-31(25(32)30(24)18-19-33-23-10-4-3-5-11-23)13-7-12-28-14-16-29(17-15-28)22-9-6-8-21(26)20-22;/h3-6,8-11,20H,2,7,12-19H2,1H3;1H |
| Molecular Structure: |
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| Properties |
| Flash Point: | 316.4°C |
| Boiling Point: | 599.6°C at 760 mmHg |
| Appearance: | white solid |
| Biological Activity: | Serotonin 5-HT 2A receptor antagonist (K i = 5.8 nM) and inhibitor of serotonin and noradrenalin uptake (IC 50 values are 290 and 300 nM respectively). Displays no activity at 5-HT 1B and 5-HT 1D receptors. Active in models predictive of antidepressant potential. |
| Flash Point: | 316.4°C |
| Storage Temperature: | Desiccate at RT |
| Color: | white |
| Safety Data |
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