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3H-1,2,4-Triazol-3-one,2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)- (83366-66-9)

Identification
Name:3H-1,2,4-Triazol-3-one,2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-
Synonyms:Nefazodone
CAS:83366-66-9
Molecular Formula: C25H32 Cl N5 O2
Molecular Weight: 470.01
InChI: InChI=1/C25H32ClN5O2/c1-2-24-27-31(25(32)30(24)18-19-33-23-10-4-3-5-11-23)13-7-12-28-14-16-29(17-15-28)22-9-6-8-21(26)20-22/h3-6,8-11,20H,2,7,12-19H2,1H3
Molecular Structure: (C25H32ClN5O2) Nefazodone
Properties
Melting Point: 186 - 188 C
Water Solubility:Slightly soluble
Solubility:Slightly soluble
Appearance:White to off-white crystalline powder
Specification:

Side effects of Nefazodone hydrochloride (83366-66-9): Unlike most serotonin reuptake inhibitors, Nefazodone usually has no negative effects on libido or sexual functioning, and is actually sometimes used as an antidote to SSRI or SNRI induced impotence and anorgasmia in men. More serious side effects include an allergic reaction, fainting, or painful/prolonged erection. Less serious reactions of nefazodone include dizziness, lightheadedness, fatigue, upset stomach, insomnia; dry mouth; constipation; or blurred/abnormal vision.
Advantages of Nefazodone hydrochloride (83366-66-9): Nefazodone, though an antidepressant, may also be beneficial in the prophylaxis of migraines due to its antagonistic effects on the 5-HT2A and 5-HT2C receptors It has a more favorable side effect profile than amitriptyline, a tricyclic antidepressant commonly used for migraine prophylaxis.
 

Color: white
Usage:A selective serotonin 5-HT2 receptor antagonist. An antidepressant
Safety Data
Hazard Symbols
 

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