| Identification | |
| Name: | Mifepristone |
| Synonyms: | Estra-4,9-dien-3-one,11-[4-(dimethylamino)- phenyl]-17-hydroxy-17-(1-propynyl)-,(11a,- 17a)-;Mifepristone [USAN:BAN:INN];17-beta-Hydroxy-11-beta-(4-dimethylaminophenyl-1)-17-alpha-(prop-1-ynyl)oestra-4,9-dien-3-one;Mifeprex;Mifepristonum [Latin];R 38486;RU 38486;11beta-(4-(Dimethylamino)phenyl)-17beta-hydroxy-17-(1-propynyl)estra-4,9-dien-3-on;Estra-4,9-dien-3-one, 11-[4-(dimethylamino)phenyl]-17-hydroxy-17-(1-propynyl)-, (11b,17b)-;Prestwick_570;Mifegyne;(11beta,17beta)-11-(4-(Dimethylamino)-phenyl)-17-hydroxy-17-(1-propynyl)estra-4,9-dien-3-one;RU-486;RU486;11beta-(4-(Dimethylamino)phenyl)-17-hydroxy-21-methyl-19-nor-17alpha-pregna-4,9-dien-20-m-3-on;RU 486-6;17-(1-propynyl)estra-4,9-dien-3-one; |
| CAS: | 84371-65-3 |
| Molecular Formula: | C29H35NO2 |
| Molecular Weight: | 429.5937 |
| InChI: | InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1 |
| Molecular Structure: | ![(C29H35NO2) Estra-4,9-dien-3-one,11-[4-(dimethylamino)- phenyl]-17-hydroxy-17-(1-propynyl)-,(11a,- 17a)-;Mifepri...](https://img.guidechem.com/casimg/84371-65-3.gif) |
| Properties | |
| Density: | 1.18 g/cm3 |
| Stability: | Stable at normal temperatures and pressures. |
| Refractive index: | 1.623 |
| Water Solubility: | Soluble to 100 mM in DMSO and to 50 mM in Ethanol |
| Solubility: | Soluble to 100 mM in DMSO and to 50 mM in Ethanol |
| Appearance: | Pale Yellow Solid |
| Specification: |
? Mifepristone ,?its cas register number is 84371-65-3. It also can be called?(11beta,17beta)-11-(4-(Dimethylamino)-phenyl)-17-hydroxy-17-(1-propynyl)estra-4,9-dien-3-one ;?11beta-(4-(Dimethylamino)phenyl)-17-hydroxy-21-methyl-19-nor-17alpha-pregna-4,9-dien-20-m-3-on ;?17-beta-Hydroxy-11-beta-(4-dimethylaminophenyl-1)-17-alpha-(prop-1-ynyl)oestra-4,9-dien-3-one ; Corlux ; Mifegyne ; Mifeprex ; Mifepristona ; Mifepristonum . |
| Biological Activity: | Selective antagonist at progesterone (PR) and glucocorticoid (GR) receptors in vitro and in vivo . Is a silent antagonist at PR and has a higher affinity than progesterone. Has higher affinity for GR than dexamethasone. |
| Color: | Yellow powder |
| Usage: | A progesterone receptor antagonist with partial agonist activity. Abortifacient. |
| Safety Data | |
| Hazard Symbols |
T: Toxic
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