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Isoquinoline,5-[(2-methyl-1-piperazinyl)sulfonyl]- (84477-87-2)

Identification
Name:Isoquinoline,5-[(2-methyl-1-piperazinyl)sulfonyl]-
Synonyms:Piperazine,1-(5-isoquinolinylsulfonyl)-2-methyl- (9CI);1-(5-Isoquinolinylsulfonyl)-2-methylpiperazine; H 7; Protein kinase inhibitorH7
CAS:84477-87-2
Molecular Formula: C14H17 N3 O2 S
Molecular Weight: 291.36868
InChI: InChI=1S/C14H17N3O2S/c1-11-9-16-7-8-17(11)20(18,19)14-4-2-3-12-10-15-6-5-13(12)14/h2-6,10-11,16H,7-9H2,1H3
Molecular Structure: (C14H17N3O2S) Piperazine,1-(5-isoquinolinylsulfonyl)-2-methyl- (9CI);1-(5-Isoquinolinylsulfonyl)-2-methylpiperazin...
Properties
Flash Point: 253.3 ºC
Boiling Point: 495.3 ºC at 760 mmHg
Density:1.277 g/cm3
Refractive index:1.652
Water Solubility:ethanol: 20 mg/mL
Solubility:ethanol: 20 mg/mL
Biological Activity: Protein kinase inhibitor. IC 50 values for inhibition of PKC, PKG, PKA and myosin light chain kinase are 6.0, 5.8, 3.0 and 97.0 μ M respectively.
Flash Point: 253.3 ºC
Storage Temperature: 2-8°C
Safety Data