| Identification | |
| Name: | Phthalazine,1-hydrazinyl- |
| Synonyms: | 1(2H)-Phthalazinone,hydrazone (9CI); Phthalazine, 1-hydrazino- (6CI,8CI); 1-Hydrazinophthalazine;1-Phthalazinylhydrazine; Apresolin; Apresoline; Apressin; Apressin(pharmaceutical); Aprezolin; Ba 5968; C 5968; Ciba 5968; Hidralazin;Hipoftalin; Hydralazin; Hydralazine; Hypophthalin; NSC 126699 |
| CAS: | 86-54-4 |
| EINECS: | 201-680-3 |
| Molecular Formula: | C8H8 N4 |
| Molecular Weight: | 160.18 |
| InChI: | InChI=1/C8H8N4/c9-11-8-7-4-2-1-3-6(7)5-10-12-8/h1-5H,9H2,(H,11,12) |
| Molecular Structure: |  |
| Properties | |
| Stability: | No data. |
| Solubility: | Slightly soluble |
| Appearance: | Yellow needles from methanol. |
| Report: |
IARC Cancer Review: Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 , 1987,p. 222.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 24 , 1980,p. 85.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . |
| Storage Temperature: | Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage. |
| Color: | Yellow crystals White, crystalline powder |
| Usage: |
Hydralazine (CAS NO.86-54-4) inhibits DNA methyltransferase and modulates epigenetic regulation of gene expression.Used as Non-selective MAO-A/B inhibitor, semicarbazide-sensitive amine oxidase inhibitor and antihypertensive. |
| Safety Data | |
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