| Identification | |
| Name: | 1H-Indole-2-carboxylicacid,1-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydro-,(2S,3aR,7aS)- |
| Synonyms: | 1H-Indole-2-carboxylicacid, 1-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydro-,[2S-[1[R*(R*)],2a,3aa,7ab]]-;Gopten;Mavik;Odrik;RU 44570; |
| CAS: | 87679-37-6 |
| Molecular Formula: | C24H34N2O5 |
| Molecular Weight: | 430.53716 |
| InChI: | InChI=1S/C24H34N2O5/c1-3-31-24(30)19(14-13-17-9-5-4-6-10-17)25-16(2)22(27)26-20-12-8-7-11-18(20)15-21(26)23(28)29/h4-6,9-10,16,18-21,25H,3,7-8,11-15H2,1-2H3,(H,28,29)/t16-,18+,19-,20-,21-/m0/s1 |
| Molecular Structure: | ![(C24H34N2O5) 1H-Indole-2-carboxylicacid, 1-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydro-,[...](https://img.guidechem.com/casimg/87679-37-6.gif) |
| Properties | |
| Melting Point: | 122-123 oC |
| Flash Point: | 332.4 oC |
| Boiling Point: | 626 oC at 760 mmHg |
| Density: | 1.181 g/cm3 |
| Refractive index: | 1.549 |
| Water Solubility: | Insoluble in water |
| Solubility: | Insoluble in water |
| Appearance: | White powder |
| Specification: |
?Trandolapril with a CAS number of 87679-37-6, also named (2S,3aR,7aS)-1-[(2S)-2-[[(1S)-1-Ethoxycarbonyl-3-phenyl-propyl]amino]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid , is an ACE inhibitor. Trandolapril's possible drug interactions: Patients on diuretics maybe will experience an excessive reduction of blood pressure after initiation of therapy with Trandolapril. Trandolapril (CAS NO.87679-37-6) can reduce potassium loss caused by thiazide diuretics, and increase serum potassium when used alone. So hyperkalemia is a possible risk. Increased serum lithum levels can occur in patients who are also on lithium.It should?be stored in original container in a cool dark place. |
| Report: |
?Trandolapril (CAS NO.87679-37-6) acts by competitive inhibition of Angiotensin Converting Enzyme (ACE), a key enzyme in the renin-angiotensin system (RAS pathway) ,it plays a very important role in regulating blood pressure. |
| Flash Point: | 332.4 oC |
| Storage Temperature: | Room temp |
| Usage: | An antihypertensive. Angiotensin converting enzyme (ACE) inhibitor |
| Safety Data | |
 |
|
