Dismutase, superoxide (9054-89-1)

With the CAS registry number 9054-89-1, Dismutase, superoxide is also named as Superoxide dismutase. It is blue-gray powder which is an oxidoreductase that catalyzes the reaction between superoxide anions and hydrogen to yield molecular oxygen and hydrogen peroxide. The enzyme protects the cell against dangerous levels of superoxide.

The following half-reactions are Dismutase, superoxide(SOD)-catalysed dismutation of superoxide:
M⁽ⁿ⁺¹⁾⁺-SOD + O₂^- → Mn⁺-SOD + O₂
Mn⁺-SOD + O₂^- + 2H⁺ → M⁽ⁿ⁺¹⁾⁺-SOD + H₂O₂.
where M = Cu (n=1) ; Mn (n=2) ; Fe (n=2) ; Ni (n=2).

Preparation of Dismutase, superoxide: Using bovine red blood cells as raw materials, and hemoglobin are removed after washing. Then by column chromatography and dialysis, we can get the refined products.

Uses of Dismutase, superoxide: It is used in biochemical research. In clinical, it is commonly used in the treatment of systemic lupus erythematosus (SLE), dermatomyositis, rheumatoid arthritis, scleroderma, autoimmune hemolytic anemia, thrombocytopenia autoimmune and other diseases. In addition, Dismutase, superoxide is also used for anti-aging.

When you are using this chemical, please be cautious about it as the following:
It is irritating to eyes, respiratory system and skin so people should not breathe dust and avoid contact with skin and eyes. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. If you want to contact this product, you must wear suitable protective clothing.