| Identification | |
| Name: | noscapine hydrochloride hydrate |
| Synonyms: | - |
| CAS: | 912-60-7 |
| EINECS: | 213-014-9 |
| Molecular Formula: | C22H23NO7?HCl |
| Molecular Weight: | 449.88 |
| InChI: | InChI=1/C22H23NO7.ClH/c1-23-8-7-11-9-14-20(29-10-28-14)21(27-4)15(11)17(23)18-12-5-6-13(25-2)19(26-3)16(12)22(24)30-18;/h5-6,9,17-18H,7-8,10H2,1-4H3;1H/t17-,18-;/m0./s1 |
| Molecular Structure: |  |
| Properties | |
| Transport: | 1544 |
| Flash Point: | 295.7°C |
| Boiling Point: | 565.3°Cat760mmHg |
| Density: | 1.332g/cm3 |
| Packinggroup: | III |
| Biological Activity: | Opioid alkaloid with several actions. Binds to tubulin, arresting cells in mitosis and inducing apoptosis. Also is an antagonist at bradykinin receptors (pA 2 = 6.68), inhibits carbachol-stimulated phosphoinositol turnover and enhances forskolin-stimulated increases in cAMP levels in CNS tissues. Clinically used antitussive agent. |
| Flash Point: | 295.7°C |
| Storage Temperature: | 2-8°C |
| Safety Data | |
| Hazard Symbols |
Xi:Irritant
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