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1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione,4-ethyl-4-hydroxy-10-nitro-, (4S)- (91421-42-0)

Identification
Name:1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione,4-ethyl-4-hydroxy-10-nitro-, (4S)-
Synonyms:1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione,4-ethyl-4-hydroxy-10-nitro-, (S)-;9-Nitro-20(S)-camptothecin;9-Nitrocamptothecin;Orathecin;RFS 2000;
CAS:91421-42-0
Molecular Formula: C20H15N3O6
Molecular Weight: 393.35
InChI: InChI=1S/C20H15N3O6/c1-2-20(26)13-7-16-17-10(8-22(16)18(24)12(13)9-29-19(20)25)6-11-14(21-17)4-3-5-15(11)23(27)28/h3-7,26H,2,8-9H2,1H3/t20-/m1/s1
Molecular Structure: (C20H15N3O6) 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione,4-ethyl-4-hydroxy-10-nitro-, (S)-;...
Properties
Melting Point: 182-186 oC
Density:1.63g/cm3
Appearance:Yellow amorphous powder
Storage Temperature: Room temp
Usage:

Semisynthetic camptothecin which inhibits DNA topoisomerase I. Prodrug of 9-aminocamptothecin. Antineoplastic

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