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Ubenimex

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[Flash Point]

320
[Fire Fighting]

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
[Ingestion]

If swallowed, wash out mouth with water provided person is conscious. Call a physician.
[Inhalation]

If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
[Skin]

In case of contact, immediately wash skin with soap and copious amounts of water.
[Eyes]

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.
[Storage]

Keep tightly closed.
[Inhalation]

May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
[Skin]

May cause skin irritation. May be harmful if absorbed through the skin.
[Eyes]

May cause eye irritation.
[Ingestion]

May be harmful if swallowed.
[Hazards]

Emits toxic fumes under fire conditions.
[EC Safety Phrase]

22 24/25
[Personal Protection]

Protective gloves. Chemical safety goggles.
[Respirators]

Wear dust mask.
[Exposure Effects]

The chemical, physical, and toxicological properties of this product have not been thoroughly investigated. Exercise due care.
[Appearance]

white powder
[Solubility in water]

Soluble
[Melting Point]

231 - 234
[Vapor Pressure]

2E-15 (25 C)
[pKa/pKb]

3.60 (pKa)
[Heat Of Vaporization]

94.5 kJ/mol
[Usage]

An aminopeptidase inhibitor used in combination with chemotherapeutics for the maintenance and enhancement of complete remission of acute non-lymphocytic leukemia in adults.
[Product Name]

Ubenimex
[Synonyms]

3-(R)-Amino-2-(S)-hydroxy-4-phenylbutanoyl-(S)-leucine
Bestatin
N-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine
NK-421
[CAS]

"CASEN_58970-76-6.htm">58970-76-6
[Formula]

C16H24N2O4
[Molecular Weight]

308.38
[EINECS]

261-529-2
[RTECS]

OH2915000
[RTECS Class]

Drug; Reproductive Effector; Natural Product
[Merck]

12,9973
[Beilstein/Gmelin]

4704312
[Beilstein Reference]

6-14
[Small spills/leaks]

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
[Stability]

Stable at normal temperatures and pressures.
[Incompatibilities]

Strong oxidizing agents.
[Decomposition]

Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen chloride gas.