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Sinomenine

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[Flash Point]

264
[Fire Fighting]

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
[Ingestion]

If swallowed, wash out mouth with water provided person is conscious. Call a physician.
[Inhalation]

If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
[Skin]

In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
[Eyes]

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.
[Storage]

Keep tightly closed. Store in a cool dry place.
[Inhalation]

Material is irritating to mucous membranes and upper respiratory tract.
[Hazards]

Emits toxic fumes under fire conditions.
[EC Risk Phrase]

45 46 23/24/25 36/37/38
[EC Safety Phrase]

53 22 26 36/37/39 45
[Personal Protection]

Compatible chemical-resistant gloves. Chemical safety goggles.
[Respirators]

Government approved respirator.
[Exposure Effects]

May cause cancer. May cause heritable genetic damage. Toxic by inhalation, in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin. Target organ(s): Liver. Kidneys.
[Appearance]

A toxic crystalline alkaloid from the root of Sinomenium acutum, structurally related to thebaine.
[Solubility in water]

Insoluble
[Melting Point]

219 - 221
[Boiling Point]

513
[Vapor Pressure]

3E-11 (25 C)
[pKa/pKb]

9.71 (pKa)
[Heat Of Vaporization]

81.5 kJ/mol
[Usage]

Anti-inflammatory.
[Refractive Index]

 
[Product Name]

(9alpha,13alpha,14alpha)-7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-one
[Synonyms]

(9a,13a,14a)-7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-one
Cucoline
[CAS]

115-53-7
[Formula]

C19H23NO4
[Molecular Weight]

329.4
[EINECS]

204-094-6
[RTECS]

QD2170000
[RTECS Class]

Drug
[Merck]

12,8692
[Beilstein/Gmelin]

95280
[Beilstein Reference]

5-21-13-00516
[Small spills/leaks]

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
[Incompatibilities]

Strong oxidizing agents.
[Decomposition]

Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen chloride gas, Phosgene gas.