| [Fire Fighting] Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire. | |
| [Ingestion] Do not induce emesis. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents. | |
| [Inhalation] If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention. | |
| [Skin] Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse. | |
| [Eyes] If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention. | |
| [Storage] Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage. | |
| [Handling] All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood. | |
| [Inhalation] Tachypnea is common. Pulmonary hypertension has been associated with chronic use or abuse which may result from contaminants. Pulmonary edema and ards are unusual complications of severe exposure. | |
| [Skin] The skin is usually flushed and diaphoretic. | |
| [Ingestion] Vomiting, diarrhea, cramps, anorexia and gastrointestinal hemorrhage may occur. | |
| [Personal Protection] Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots. | |
| [Respirators] Use NIOSH/MSHA approved respirator appropriate for exposure of concern. | |
| [Exposure Effects] Severe elevated body temperature may develop. Elevated blood pressure and rapid heart rate are common. Agitation, confusion, paranoia, delirium, hallucinations, restlessness, hyperactivity, talkativeness, irritability, insomnia, and headache are common. Chorea, dystonia, fasciculations, muscle rigidity, tics, and tremors may develop. Seizures and coma may occur with severe intoxication. Other neurological effects have included stroke and cerebral vasculitis. Serotonin syndrome has occurred. | |
| [Appearance] Crystals. | |
| [Solubility in water] Insoluble | |
| [Melting Point] 218 | |
| [Boiling Point] 322 | |
| [pKa/pKb] 3.50 (pKb) | |
| [Partition Coefficient] 1.27 | |
| [Usage] Medication. | |
| [Product Name] Pemoline | |
| [Synonyms] 2-Amino-5-phenyl-4(5h)-oxazolone Azoksodon Azoxodone Centramin Constimol Cs 293 | |
| [CAS] "CASEN_2152-34-3.htm">2152-34-3 | |
| [Formula] C9H8N2O2 | |
| [Molecular Weight] 176.17 | |
| [EINECS] 218-438-8 | |
| [RTECS] RQ2975000 | |
| [RTECS Class] Drug; Reproductive Effector; Human Data | |
| [Merck] 12,7206 | |
| [Beilstein/Gmelin] 151559 | |
| [Beilstein Reference] 4-27-00-05622 | |
| [Small spills/leaks] Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces. | |
| [Stability] No data. | |
| [Incompatibilities] Strong oxidizing agents. |
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