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Erythromycin ethylsuccinate

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[Fire Fighting]

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.
[Ingestion]

Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
[Inhalation]

If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
[Skin]

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
[Eyes]

If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.
[Storage]

Keep in a cool, dry, well-ventilated area in a sealed container.
[Handling]

Keep container closed when not in use. Avoid contact. Follow label directions.
[Personal Protection]

Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
[Respirators]

Where environmental controls are lacking or in an enclosed space, use a NIOSH/MSHA approved respirator for dust.
[Exposure Effects]

Allergic skin and respiratory reactions have been reported.
[Appearance]

Crystals.
[Solubility in water]

Insoluble
[Melting Point]

109 - 110
[pKa/pKb]

6.42 (pKb)
[Usage]

Medication.
[Product Name]

Erythromycin ethylsuccinate
[Synonyms]

Eritrocina
Erythromycin, 2'-(ethyl butanedioate)
Ethyl [(2R,3S,4R,6S)-4-dimethylamino-2-[[(3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-14-ethyl-7,12,13-trihydroxy-4-[(2S,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyl-oxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-2,10-dioxo-1-oxacyclotetradec-6-yl]oxy]-6-methyl-oxan-3-yl] butanedioate
Monomycin
Paediathrocin
Succinic acid, monoester with erythromycin
[CAS]

1264-62-6
[Formula]

C43H75NO16
[Molecular Weight]

862.06
[EINECS]

215-033-8
[RTECS]

WM9800000
[RTECS Class]

Drug; Human Data
[Beilstein/Gmelin]

77638
[Beilstein Reference]

4-18-00-07416
[Small spills/leaks]

Ventilate area. Use protective eqiupment. Sweep or vacuum up. Do not creat dust. Place in a dry container for disposal. Clean spill area with water.
[Stability]

Stable.
[Incompatibilities]

Strong oxidizing agents.
[Decomposition]

None reported.