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trans-Dichlorodiamineplatinum(II)

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[Fire Fighting]

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
[Fire Potential]

Non-Combustible
[Ingestion]

Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
[Inhalation]

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
[Skin]

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
[Eyes]

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
[Storage]

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
[Handling]

Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
[Inhalation]

May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
[Skin]

May cause skin irritation.
[Eyes]

May cause eye irritation.
[Ingestion]

May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
[UN (DOT)]

3288
[Personal Protection]

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
[Respirators]

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
[Exposure Effects]

Possible risk of irreversible effects.
[Exposure limit(s)]

IDHL: 4 mg/m3
[Appearance]

Deep yellow crystals.
[Solubility in water]

Slightly soluble
[Melting Point]

340
[Density]

3.746 g/cm3
[Usage]

After undergoing hydrolysis, it reacts with dna to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of dna.
[Refractive Index]

1.706
[Product Name]

trans-Diammineplatinum(II) dichloride
[Synonyms]

NSC 131558
trans-Diamminedichloroplatinum
trans-Diamminedichloroplatinum(II)
trans-Dichlorodiammineplatinum(II)
trans-Platinum(II)diamminedichloride
[CAS]

"CASEN_14913-33-8.htm">14913-33-8
[Formula]

Cl2H6N2Pt
[Molecular Weight]

300.04000000000002
[EINECS]

238-980-9
[RTECS]

TP2455000
[RTECS Class]

Tumorigen; Drug; Mutagen
[Beilstein/Gmelin]

2520 (G)
[Small spills/leaks]

Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
[Incompatibilities]

Oxidizing agents.
[Stability]

Stable under normal temperatures and pressures.
[Decomposition]

Hydrogen chloride, nitrogen oxides, irritating and toxic fumes and gases, nitrogen.
[Combustion Products]

Toxic gases and vapors (such as chlorine) may be released when chlorine-containing soluble platinum salts decompose.
[UN Number]

3288
[Hazard Class]

6.1
[Packing Group]

I; II; III