Home >> msds >> Hygromycin B

Hygromycin B

Print        Favorite
[Fire Fighting]

Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher.
[Ingestion]

If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. MMEDIATELY transport the victim to a hospital.
[Inhalation]

IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
[Skin]

IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.
[Eyes]

First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.
[Storage]

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
[Handling]

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
[Inhalation]

May be irritating to mucous membranes and upper respiratory tract. May be fatal if inhaled. May cause allergic reactions.
[Skin]

Causes irritation. May be fatal if absorbed through the skin. May cause allergic skin reaction.
[Eyes]

Causes severe irritation.
[Ingestion]

May be fatel if swallowed.
[EC Risk Phrase]

26/27/28 41 42/43
[EC Safety Phrase]

22 26 28 36/37/39 45
[UN (DOT)]

3462
[Personal Protection]

If Tyvek-type disposable protective clothing is not worn during handling of this chemical, wear disposable Tyvek-type sleeves taped to your gloves.
[Respirators]

Wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter). Splash proof safety goggles should be worn while handling this chemical. Alternatively, a full face respirator, equipped as above, may be used to provide simultaneous eye and respiratory protection.
[Exposure Effects]

Targets ears. Signs and symptoms of exposure include dermatitis, conjunctivitis, burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea and vomiting. Repeated exposure can cause hearing loss.
[Melting Point]

160
[pKa/pKb]

4.50 (pKb)
[Usage]

Antibiotic that kills bacteria, fungi and higher eukaryotic cells by inhibiting protein synthesis.
[Product Name]

O-6-Amino-6-deoxy-L-glycero-D-galacto-heptopyranosylidene-(1-2-3)-o-beta-D-talopyranosyl-(1-5)-2-deoxy-N3-methyl-D-streptamine
[Synonyms]

5-O-(2,3-O-(6-Amino-6-desoxyheptapyranosyliden)-beta-D-talopyranosyl)-desoxy-N'-methyl-D-streptamin
Antihelmycin
Hydromycin B
Hygromix 2.4
Hygromix 8
Hygrovetine
[CAS]

"CASEN_31282-04-9.htm">31282-04-9
[Formula]

C20H37N3O13
[Molecular Weight]

527.53
[EINECS]

250-545-5
[RTECS]

WK2130000
[RTECS Class]

Drug; Mutagen; Natural Product
[Merck]

12,4901
[Beilstein/Gmelin]

6755837
[Small spills/leaks]

If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
[Stability]

Stable at normal temperatures and pressures.
[Incompatibilities]

Strong oxidizing agents.
[Decomposition]

Oxides of carbon and nitrogen.
[UN Number]

3462
[Hazard Class]

6.1
[Packing Group]

I