Home >> msds >> 5-Fluorouracil

5-Fluorouracil

Print        Favorite
[Flash Point]

280
[Fire Fighting]

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing media: Use water spray, dry chemical, or carbon dioxide.
[Ingestion]

Get medical aid. Wash mouth out with water.
[Inhalation]

Remove from exposure to fresh air immediately. Get medical aid.
[Skin]

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
[Eyes]

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
[Storage]

Store in a cool, dry place. Store in a tightly closed container.
[Handling]

Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Store protected from light. Use only in a chemical fume hood.
[Inhalation]

Harmful if inhaled. Causes respiratory tract irritation.
[Skin]

Causes skin irritation. Harmful if absorbed through the skin.
[Eyes]

May cause eye irritation.
[Ingestion]

Harmful if swallowed. Causes gastrointestinal irritation with nausea, vomiting and diarrhea.
[Hazards]

Emits very toxic fumes of flourides and nitrogen oxides when heated to decomposition. Avoid decomposing heat.
[EC Risk Phrase]

R 46 60 61 23/24/25
[EC Safety Phrase]

S 53 45
[UN (DOT)]

2811
[Personal Protection]

Eyes: Wear chemical goggles. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear a chemical apron.
[Respirators]

A NIOSH/MSHA approved air purifying dust or mist respirator or European Standard EN 149.
[Exposure Effects]

Prolonged or repeated exposure may cause adverse reproductive effects.
[Poison Class]

1*
[Appearance]

White to nearly white crystalline powder; practically odorless.
[Solubility in water]

Very soluble
[Melting Point]

282 - 283
[Boiling Point]

347
[pKa/pKb]

7.88 (pKa)
[Partition Coefficient]

-.78
[Heat Of Vaporization]

[Usage]

Immunosuppressive agent.
[Product Name]

5-Fluoropyrimidine-2,4-dione
[Synonyms]

5-Fluoro-1H-pyrimidine-2,4-dione
5-Fluoro-2,4(1H,3H)-pyrimidinedione
[CAS]

"CASEN_51-21-8.htm">51-21-8
[Formula]

C4H3FN2O2
[Molecular Weight]

130.08000000000001
[EINECS]

200-085-6
[RTECS]

YR0350000
[RTECS Class]

Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data; Primary Irritant
[Merck]

13,4208
[Beilstein/Gmelin]

127172
[Beilstein Reference]

5-34-06-00271
[EC Class]

harmful
[Small spills/leaks]

Vacuum or sweep up material and place into a suitable disposal container.
[Disposal Code]

3
[Stability]

Stable under normal temperatures and pressures.
[Incompatibilities]

Strong oxidizing agents.
[Decomposition]

Nitrogen oxides, carbon monoxide, carbon dioxide, hydrogen fluoride.
[UN Number]

2811
[HS Code]

2933 59 95