| [Flash Point] 301 | |
| [Fire Fighting] This compound is not very flammable but any fire involving this compound may produce dangerous vapors. You should evacuate the area. All firefighters should wear full-body protective clothing and use self-contained breathing apparatuses. You should extinguish any fires involving this chemical with a dry chemical, carbon dioxide, foam, or halon extinguisher. | |
| [Ingestion] If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. MMEDIATELY transport the victim to a hospital. | |
| [Inhalation] IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used. | |
| [Skin] IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. | |
| [Eyes] First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. | |
| [Storage] Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage. | |
| [Handling] All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood. | |
| [Inhalation] May cause gastrointestinal discomfort and possibly ulcerations. May aggravate psychiatric disturbances, epilepsy, and parkinsonism. May cause drowsiness and headache. | |
| [Skin] See inhalation. | |
| [Eyes] See inhalation | |
| [Personal Protection] Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots. | |
| [Respirators] Wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter). | |
| [Exposure Effects] Disorientation, mental confusion, and lethargy have been reported. Headache, dizziness, vertigo, and stupor may also occur, as these have been noted at therapeutic doses. | |
| [Appearance] Crystals. | |
| [Solubility in water] Slightly soluble | |
| [Melting Point] 163 | |
| [Boiling Point] 575 | |
| [Vapor Pressure] 5E-14 (25 C) | |
| [pKa/pKb] 4.17 (pKa) | |
| [Partition Coefficient] 4.27 | |
| [Heat Of Vaporization] 90.6 kJ/mol | |
| [Usage] Medication. | |
| [Product Name] 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid | |
| [Synonyms] 1-(p-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid 1H-Indole-3-acetic acid, 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl alpha-(1-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-Indolyl)acetic acid Indomecol N-p-Chlorbenzoyl-5-methoxy-2-methylindole-3-acetic acid | |
| [CAS] "CASEN_53-86-1.htm">53-86-1 | |
| [Formula] C19H16ClNO4 | |
| [Molecular Weight] 357.79 | |
| [EINECS] 200-186-5 | |
| [RTECS] NL3500000 | |
| [RTECS Class] Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data | |
| [Merck] 12,4998 | |
| [Beilstein/Gmelin] 497341 | |
| [Beilstein Reference] 5-22-05-00239 | |
| [Small spills/leaks] Should a spill occur while you are handling this chemical, you should dampen the solid spill material with alcohol, then transfer the dampened material to a suitable container. Use absorbent paper dampened with alcohol to pick up any remaining material. Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with alcohol followed by washing with a strong soap and water solution. Do not reenter the contaminate area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. | |
| [Stability] Sensitive to light stable in neutral or slightly acidic media, decomp by strong alkali stable in air and in heat under usual prevailing temperature conditions compressed tablets harden on storage. |
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