| [Storage] Store at -20 C, protect from light. | |
| [Appearance] White solid. | |
| [Solubility in water] Insoluble | |
| [Melting Point] 242 - 243 | |
| [Vapor Pressure] 1.1E-14 (25 C) | |
| [Density] 1.226 g/cm3 (20 C) | |
| [pKa/pKb] 14.74 | |
| [Partition Coefficient] 3.42 | |
| [Usage] A cardiotonic steroid isolated from bufo species toads that potently inhibits ouabain-sensitive na+,k+-atpase activity. Induces apoptosis in various human cell lines such as leukemia hl60 and u937 cells by altering the expression of apoptosis-related genes. | |
| [Product Name] 3-b,14-Dihydroxy-5-beta-bufa-20,22-dienolide | |
| [Synonyms] 3-beta,14-Dihydroxy-5-beta-bufa-20,22-dienolide 5-(3,14-Dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl)pyran-2-one Bufa-20,22-dienolide, 3,14-dihydroxy-, (3-beta,5-beta)- Bufalin | |
| [CAS] "CASEN_465-21-4.htm">465-21-4 | |
| [Formula] C24H34O4 | |
| [Molecular Weight] 386.53 | |
| [RTECS] EI2962500 | |
| [Merck] 12,1493 | |
| [Beilstein/Gmelin] 5141601 | |
| [Incompatibilities] Air sensitive. | |
| [Stability] Stable for a year if stored as directed. |
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