| [Flash Point] 43 | |
| [Fire Fighting] Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. A water spray may also be used. | |
| [Fire Fighting] Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing media: For small fires, use water spray, dry chemical, carbon dioxide or chemical foam. | |
| [Fire Potential] This material is probably combustible. | |
| [Ingestion] DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. | |
| [Ingestion] If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid. | |
| [Inhalation] IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used. | |
| [Inhalation] May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. | |
| [Inhalation] Remove from exposure to fresh air immediately. Get medical aid if cough or other symptoms appear. | |
| [Skin] May cause skin irritation. No information reported. | |
| [Skin] Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. | |
| [Skin] IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. | |
| [Eyes] First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. | |
| [Eyes] Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. | |
| [Eyes] Dust may cause mechanical irritation. No information reported. | |
| [Storage] Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage. | |
| [Storage] Store in a cool, dry, well-ventilated area away from incompatible substances. | |
| [Handling] Wash hands before eating. Use with adequate ventilation. Avoid contact with skin and eyes. Avoid ingestion and inhalation. | |
| [Handling] All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood. | |
| [Ingestion] May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated. | |
| [Inhalation] Symptoms of exposure to this compound may include fever, nausea, vomiting, diarrhea, chills, cough, dyspnea, chest pain, pulmonary infiltration, hepatitis, eosinophilia, interstitial pneumonitis or fibrosis, hemolytic anemia, megaloblastic anemia, cholestatic jaundice, granulocytopenia, leukopenia and headache. | |
| [Skin] See inhalation. | |
| [Eyes] See inhalation | |
| [Personal Protection] Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots. | |
| [Personal Protection] Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. | |
| [Respirators] Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary. | |
| [Respirators] Wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter). | |
| [Exposure Effects] with therapeutic use - peripheral neuropathies have been reported as a complication of treatment with nitrofurantoin, especially in patients with pre-existing renal dysfunction. | |
| [Appearance] Odorless lemon yellow crystals or fine yellow powder. Bitter taste. | |
| [Appearance] Yellow to green liquid. A by-product of the resin, balsam is a pale yellow to clear oil, steam-distilled from the needles of the Canadian balsam. It has a pleasing sweet, woody, balsamic scent | |
| [Solubility in water] (mg/100 ml): water | |
| [Melting Point] 272 | |
| [Density] 0.915 g/cm3 (20 C) | |
| [Density] 1.6 g/cm3 | |
| [pKa/pKb] 7.2 (pKa) | |
| [Partition Coefficient] -.47 | |
| [Usage] Ingredient in expectorants, tonic to treat pellagra, a pain relief formula, and and expectorant. | |
| [Usage] Medication. | |
| [Refractive Index] 1.52 (20 C) | |
| [Product Name] Nitrofurantoin | |
| [Synonyms] 1-[(5-Mitrofuran-2-yl)methylideneamino]imidazolidine-2,4-dione Balsam of fir Berkfuran Chemiofuran Cyantin Fir balsam absolute Furadantin Nitrofurantoin | |
| [CAS] "CASEN_67-20-9.htm">67-20-9 | |
| [CAS] "CASEN_8007-47-4.htm">8007-47-4 | |
| [Formula] C8H6N4O5 | |
| [Molecular Weight] 238.16 | |
| [EINECS] 200-646-5 | |
| [EINECS] 232-362-2 | |
| [RTECS] CP2352500 | |
| [RTECS] MU2800000 | |
| [RTECS Class] Other | |
| [RTECS Class] Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data | |
| [Merck] 12,6696 | |
| [Merck] 13,948 | |
| [Beilstein/Gmelin] NA | |
| [Beilstein/Gmelin] 290482 | |
| [Beilstein Reference] 5-24-05-00224 | |
| [Small spills/leaks] Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. | |
| [Small spills/leaks] If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. | |
| [Stability] Sensitive to heat discolored by alkali and by exposure to light, and is decomp upon contact with metals other than stainless steel or aluminum. | |
| [Incompatibilities] Sensitive to light Incompatible with alkalis Incompatible with strong oxidizers and strong acids. | |
| [Stability] Stable under normal temperatures and pressures. | |
| [Incompatibilities] Strong oxidizing agents. | |
| [Decomposition] Oxides of carbon. |
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