| [Fire Fighting] Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Extinguishing media: Substance is noncombustible; use agent most appropriate to extinguish surrounding fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam. | |
| [Fire Potential] This material is probably combustible. | |
| [Ingestion] Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. | |
| [Inhalation] Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration. | |
| [Skin] Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. | |
| [Eyes] Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. | |
| [Storage] Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Refrigerator (approx 4 C). | |
| [Handling] Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. | |
| [Inhalation] May cause respiratory tract irritation. May cause effects similar to those described for ingestion. | |
| [Skin] May cause skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. May cause dermatitis. | |
| [Eyes] Causes mild eye irritation. May cause chemical conjunctivitis. | |
| [Ingestion] May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause liver damage. May cause bone marrow depression. | |
| [Personal Protection] Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. | |
| [Respirators] A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use. | |
| [Exposure Effects] Repeated exposure may cause sensitization dermatitis. Reproductive effects have been reported in animals. | |
| [Appearance] Crystals (from aqueous ethanol) or fluffy white powder. | |
| [Melting Point] 210 - 212 | |
| [Heat Of Vaporization] | |
| [Usage] Treatment of leukaemia, especially acute non-lymphoblastic leukaemia. | |
| [Product Name] 1-beta-D-Arabinofuranosylcytosine hydrochloride | |
| [Synonyms] 4-Amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one hydrochloride Cylocide Cytosine, 1-beta-D-arabinofuranosyl, monohydrochloride Iretin | |
| [CAS] "CASEN_69-74-9.htm">69-74-9 | |
| [Formula] C9H14ClN3O5 | |
| [Molecular Weight] 279.68 | |
| [EINECS] 200-713-9 | |
| [RTECS] HA5500000 | |
| [RTECS Class] Drug; Mutagen; Reproductive Effector; Primary Irritant | |
| [Beilstein/Gmelin] 4045072 | |
| [Small spills/leaks] Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation. | |
| [Incompatibilities] Oxidizing agents. | |
| [Stability] Stable at room temperature in closed containers under normal storage and handling conditions. | |
| [Decomposition] Hydrogen chloride, carbon monoxide, oxides of nitrogen, irritating and toxic fumes and gases, carbon dioxide. |
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