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4-Methylpyrazole

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[Flash Point]

96
[Fire Fighting]

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
[Ingestion]

Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
[Inhalation]

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
[Skin]

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
[Eyes]

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
[Storage]

Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.
[Handling]

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Wash clothing before reuse.
[Ingestion]

Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May be harmful if swallowed.
[Inhalation]

Causes respiratory tract irritation.
[Skin]

Causes skin irritation.
[Eyes]

Causes eye irritation.
[EC Risk Phrase]

R 22 36/37/38
[EC Safety Phrase]

S 26 36/37/39
[Personal Protection]

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
[Respirators]

Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
[Appearance]

Yellow liquid.
[Solubility in water]

Soluble
[Melting Point]

16 - 19
[Boiling Point]

244
[Vapor Pressure]

0.05 (25 C)
[Density]

1.0183 g/cm3 (17 C)
[pKa/pKb]

10.79 (pKb)
[Partition Coefficient]

.78
[Heat Of Vaporization]

46.1 kJ/mol
[Usage]

Antidot for ethylene glycol poisoning treatment.
[Vapor Density]

2.83
[Refractive Index]

1.4895 (16.7 C)
[Product Name]

Fomepizol
[Synonyms]

4-Methyl-1H-pyrazole
4-Methylpyrazole
4-MP
Fomepizole
[CAS]

"CASEN_7554-65-6.htm">7554-65-6
[Formula]

C4H6N2
[Molecular Weight]

82.1
[EINECS]

231-445-0
[RTECS]

UQ7350000
[RTECS Class]

Other
[Merck]

13,4242
[Beilstein/Gmelin]

105204
[Beilstein Reference]

5-23-05-00031
[Small spills/leaks]

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.
[Stability]

Stable under normal temperatures and pressures.
[Incompatibilities]

Strong oxidizing agents - strong acids - acid chlorides.
[Decomposition]

Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.