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Nalmefene

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[Fire Fighting]

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.
[Ingestion]

Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
[Inhalation]

If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
[Skin]

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
[Eyes]

If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.
[Storage]

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
[Handling]

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
[Personal Protection]

Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
[Respirators]

Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
[Exposure Effects]

The toxicological properties of this material have not been investigated.
[Solubility in water]

Insoluble
[Melting Point]

188 - 190
[Vapor Pressure]

6.0e-14
[pKa/pKb]

6.44 (pKb)
[Usage]

Medication.
[Product Name]

Nalmefene
[Synonyms]

(5alpha)-17-(Cyclopropylmethyl)-4,5-epoxy-6-methylenemorphinon-3,14-diol
17-(Cyclopropylmethyl)-4,5alpha-epoxy-6-methylenemorphinan-3,14-diol
6-Deoxo-6-methylenenaltrexone
6-Desoxy-6-methylenenaltrexone
9a-(Cyclopropylmethyl)-4,5alpha-epoxy-6-methylen-3,14-morphinandiol
Nalmetrene
[CAS]

"CASEN_55096-26-9.htm">55096-26-9
[Formula]

C21H25NO3
[Molecular Weight]

339.43
[Merck]

12,6447
[Beilstein/Gmelin]

4941054
[Small spills/leaks]

Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
[Stability]

No data.
[Incompatibilities]

Strong oxidizing agents.