Home >> msds >> Omeprazole

Omeprazole

Print        Favorite
[Fire Fighting]

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.
[Ingestion]

Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
[Inhalation]

If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
[Skin]

Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.
[Eyes]

If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.
[Storage]

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
[Handling]

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
[Skin]

Lichen spinulosis and exfoliative dermatitis have been associated with omeprazole therapy.
[Personal Protection]

Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
[Respirators]

Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
[Exposure Effects]

confusion, somnolence, headache, dizziness and blurred vision have been reported with therapeutic use and may follow overdoses of omeprazole. No embryonic, teratogenic, or fetotoxic effects have been seen in animals tested. <br>Omeprazole has been shown to cross the placenta in animals and humans.
[Appearance]

Crystals from acetonitrile.
[Solubility in water]

Slightly soluble
[Melting Point]

144 - 146
[Density]

1.329 g/cm3
[pKa/pKb]

4.92 (pKb)
[Partition Coefficient]

2.38
[Usage]

Medication.
[Product Name]

5-Methoxy-2-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methylsulfinyl]-3H-benzoimidazole
[Synonyms]

1H-Benzimidazole, 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-
Gastrozole
lcometion
Prilosec
Roweprazol
Sanamidol
[CAS]

"CASEN_73590-58-6.htm">73590-58-6
[Formula]

C17H19N3O3S
[Molecular Weight]

345.42
[RTECS]

DD9087000
[RTECS Class]

Drug; Mutagen; Reproductive Effector; Human Data
[Merck]

12,6977
[Beilstein/Gmelin]

3628192
[Small spills/leaks]

Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
[Stability]

No data.
[Incompatibilities]

Strong oxidizing agents.