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Domperidone

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[Fire Fighting]

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
[Ingestion]

If swallowed, wash out mouth with water provided person is conscious. Call a physician immediately.
[Inhalation]

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
[Skin]

In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
[Eyes]

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.
[Storage]

Keep tightly closed.
[Inhalation]

May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
[Skin]

May cause skin irritation. May be harmful if absorbed through the skin.
[Eyes]

May cause eye irritation.
[Ingestion]

May be harmful if swallowed.
[Hazards]

Emits toxic fumes under fire conditions.
[Personal Protection]

Compatible chemical-resistant gloves.
[Respirators]

Government approved respirator.
[Exposure Effects]

Harmful. Possible risk of harm to the unborn child. Possible risk of impaired fertility. Target organ(s): G.I. System.
[Appearance]

White powder.
[Solubility in water]

Insoluble
[Melting Point]

236 - 239
[pKa/pKb]

4.80 (pKb)
[Usage]

Peripheral dopamine receptor antagonist that does not cross the blood-brain barrier; anti-emetic.
[Product Name]

Domperidone
[Synonyms]

4-(5-Chloro-2-oxo-1-benzimidazolinyl)-1-[3-(2-oxobenzimidazolinyl)propyl]piperidine
5-Chloro-1-(1-(3-(2-oxo-1-benzimidazolinyl)propyl)-4-piperidyl)-2-benzimidazolinone
KW-5338
Motilium
Peridon
[CAS]

"CASEN_57808-66-9.htm">57808-66-9
[Formula]

C22H24ClN5O2
[Molecular Weight]

425.92
[EINECS]

260-968-7
[RTECS]

DE2275900
[RTECS Class]

Drug; Reproductive Effector; Human Data
[Merck]

12,3476
[Beilstein/Gmelin]

903774
[Beilstein Reference]

5-24-02-00402
[Small spills/leaks]

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
[Stability]

Stable at normal temperatures and pressures.
[Incompatibilities]

Strong oxidizing agents.
[Decomposition]

Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen chloride gas.