Home >> msds >> Leflunomide

Leflunomide

Print        Favorite
[Flash Point]

129
[Fire Fighting]

Extinguish with carbon dioxide, dry chemical powder or appropriate foam. Water spray. Wear self-contained breathing apparatus and protective clothing to prevent contact with the skin and eyes.
[Storage]

Store in original container in a cool dark place.
[Inhalation]

Remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen. Seek medical attention.
[Skin]

Immediately wash skin with soap and copious amounts of water for at least 15 minutes. If irritation persists, seek medical attention.
[Eyes]

Immediately flush eyes with copious amounts of water for at least 15 minutes. Seek medical advice.
[Ingestion]

If swallowed, wash out mouth with water, provided person is conscious. Seek medical advice.
[Personal Protection]

Wear self-contained breathing apparatus, rubber boots & heavy rubber gloves.
[Solubility in water]

Insoluble
[Boiling Point]

289
[Vapor Pressure]

0.0022 (25 C)
[Density]

1.392 g/cm3 (20 C)
[pKa/pKb]

11.45 (pKa)
[Partition Coefficient]

1.95
[Heat Of Vaporization]

52.9 kJ/mol
[Usage]

Used in active moderate to severe rheumatoid arthritis and psoriatic arthritis.
[Product Name]

Leflunomide
[Synonyms]

4-Isoxazolecarboxamide, 5-methyl-N-(4-(trifluoromethyl)phenyl)-
5-Methylisoxazole-4-carboxylic acid (4-trifluoromethyl)anilide
5-Methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamide
Arava
HWA-486
[CAS]

"CASEN_75706-12-6.htm">75706-12-6
[Formula]

C12H9F3N2O2
[Molecular Weight]

270.20999999999998
[RTECS]

NY2354200
[Merck]

12,10407
[Small spills/leaks]

Sweep-up/absorb in suitable material, place in a container and hold for disposal. Avoid raising dust. Ventilate area and wash spill site after pickup is complete.
[Combustion Products]

Emits toxic fumes under fire conditions.