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Metformin hydrochloride (1115-70-4)

Identification
Name:Metformin hydrochloride
Synonyms:Diaformin;Dialon;Diformin;Diformin Retard;Dimefor;Fornidd;Geamet;Glucomin;Glucomine;Gluconil;Glucophage;Glucophage 850;Glucophage Forte;Glucophage Retard;Glucophage SR;Glufor;Gluformin;Glumeformin;Glumetza;Glumin;Glupermin;Glyceriphage;Glyciphage;Glycon;Metomin;Miformin;N,N-Dimethylbiguanide hydrochloride;N,N-Dimethylbiguanidinium chloride;N1,N1-Dimethylbiguanide hydrochloride;Orabet;Siamformet;Walaphage;Biguanide, 1,1-dimethyl-, monohydrochloride(8CI);Imidodicarbonimidic diamide, N,N-dimethyl-, monohydrochloride (9CI);1,1-Dimethylbiguanide hydrochloride;
CAS:1115-70-4
EINECS: 214-230-6
Molecular Formula: C4H12ClN5
Molecular Weight: 165.62
InChI: InChI=1/C4H11N5.ClH/c1-9(2)4(7)8-3(5)6;/h1-2H3,(H5,5,6,7,8);1H
Molecular Structure: (C4H12ClN5) Diaformin;Dialon;Diformin;Diformin Retard;Dimefor;Fornidd;Geamet;Glucomin;Glucomine;Gluconil;Glucoph...
Properties
Solubility:Soluble in water, 95% alcohol. Practically insoluble in ether, chloroform.
Appearance:crystalline solid
Specification:

? Metformin hydrochloride , with CAS number of 1115-70-4, can be called 1,1-Dimethyl-biguanidhydrochloride ; Diabefagos ; Diformin ; Dimethylbiguanidehydrochloride ; Dimethyldiguanidinehydrochloride . Metformin hydrochloride (CAS NO.1115-70-4) is an oral hypoglycemic agent.

Biological Activity: Antidiabetic agent; lowers plasma glucose levels and improves insulin sensitivity. Inhibits hepatic gluconeogenesis via activation of the LKB1/AMPK pathway. Displays antiproliferative effects in cancer cell lines.
Color: Prisms from water, mp 232 deg C
Crystals from propanol, mp 218-220 deg C
Usage:

An oral hypoglycemic agent

Safety Data
Hazard Symbols Xn:Harmful