| Identification | |
| Name: | Metformin hydrochloride |
| Synonyms: | Diaformin;Dialon;Diformin;Diformin Retard;Dimefor;Fornidd;Geamet;Glucomin;Glucomine;Gluconil;Glucophage;Glucophage 850;Glucophage Forte;Glucophage Retard;Glucophage SR;Glufor;Gluformin;Glumeformin;Glumetza;Glumin;Glupermin;Glyceriphage;Glyciphage;Glycon;Metomin;Miformin;N,N-Dimethylbiguanide hydrochloride;N,N-Dimethylbiguanidinium chloride;N1,N1-Dimethylbiguanide hydrochloride;Orabet;Siamformet;Walaphage;Biguanide, 1,1-dimethyl-, monohydrochloride(8CI);Imidodicarbonimidic diamide, N,N-dimethyl-, monohydrochloride (9CI);1,1-Dimethylbiguanide hydrochloride; |
| CAS: | 1115-70-4 |
| EINECS: | 214-230-6 |
| Molecular Formula: | C4H12ClN5 |
| Molecular Weight: | 165.62 |
| InChI: | InChI=1/C4H11N5.ClH/c1-9(2)4(7)8-3(5)6;/h1-2H3,(H5,5,6,7,8);1H |
| Molecular Structure: |  |
| Properties | |
| Solubility: | Soluble in water, 95% alcohol. Practically insoluble in ether, chloroform. |
| Appearance: | crystalline solid |
| Specification: |
? Metformin hydrochloride , with CAS number of 1115-70-4, can be called 1,1-Dimethyl-biguanidhydrochloride ; Diabefagos ; Diformin ; Dimethylbiguanidehydrochloride ; Dimethyldiguanidinehydrochloride . Metformin hydrochloride (CAS NO.1115-70-4) is an oral hypoglycemic agent. |
| Biological Activity: | Antidiabetic agent; lowers plasma glucose levels and improves insulin sensitivity. Inhibits hepatic gluconeogenesis via activation of the LKB1/AMPK pathway. Displays antiproliferative effects in cancer cell lines. |
| Color: | Prisms from water, mp 232 deg C Crystals from propanol, mp 218-220 deg C |
| Usage: | An oral hypoglycemic agent |
| Safety Data | |
| Hazard Symbols |
Xn:Harmful
|
 |
|
