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Entecavir (142217-69-4)

Identification
Name:Entecavir
Synonyms:2-amino-9-[(3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidene-cyclopentyl]-3H-purin-6-one;ETV;6H-Purin-6-one, 2-amino-1,9-dihydro-9-((1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-;2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidene-cyclopentyl]-3H-purin-6-one;SQ 34676;BMS 200475;Baraclude;6H-Purin-6-one,2-amino-1,9-dihydro-9- [(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2- methylenecyclopentyl]-;Taizhou hikong chemical sell Entecavir;Entecavi;Enteca;Entecavir(monohydrate)--Crude Product;
CAS:142217-69-4
Molecular Formula: C12H15N5O3
Molecular Weight: 277.28
InChI: InChI=1/C12H15N5O3/c1-5-6(3-18)8(19)2-7(5)17-4-14-9-10(17)15-12(13)16-11(9)20/h4,6-8,18-19H,1-3H2,(H3,13,15,16,20)/t6-,7+,8-/m0/s1
Molecular Structure: (C12H15N5O3) 2-amino-9-[(3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidene-cyclopentyl]-3H-purin-6-one;ETV;6H-Puri...
Properties
Density:1.81g/cm3
Refractive index:1.837
Solubility:In water, 2.4X10+3 mg/L, temp not specified
Appearance:white to off-white/yellow crystalline powder
Color: White to off white powder
Usage:

 Entecavir (CAS NO.142217-69-4) is used to treat chronic hepatitis B. And it also helps prevent the hepatitis B virus from multiplying and infecting new liver cells. Besides, Entecavir is also indicated for the treatment of chronic hepatitis B in adults with HIV/AIDS infection, but Entecavir is not active against HIV.

Safety Data