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2-Quinolinecarboxylicacid, 7-chloro-4-hydroxy- (18000-24-3)

Identification
Name:2-Quinolinecarboxylicacid, 7-chloro-4-hydroxy-
Synonyms:Kynurenicacid, 7-chloro- (6CI);Quinaldic acid, 7-chloro-4-hydroxy- (8CI);7-Chloro-4-hydroxyquinaldic acid;7-Chlorokynurenic acid;7-Chloroquinurenicacid;NSC 149792;
CAS:18000-24-3
EINECS: 241-913-6
Molecular Formula: C10H6ClNO3
Molecular Weight: 223.61254
InChI: InChI=1S/C10H6ClNO3/c11-5-1-2-6-7(3-5)12-8(10(14)15)4-9(6)13/h1-4H,(H,12,13)(H,14,15)
Molecular Structure: (C10H6ClNO3) Kynurenicacid, 7-chloro- (6CI);Quinaldic acid, 7-chloro-4-hydroxy- (8CI);7-Chloro-4-hydroxyquinaldic...
Properties
Density:1.549 g/cm3
Refractive index:1.648
Water Solubility:Soluble in DMSO (10 mg/ml-clear, colorless to faint yellow solution)
Solubility:Soluble in DMSO (10 mg/ml-clear, colorless to faint yellow solution)
Appearance:White to yellowish powder
Biological Activity: NMDA receptor antagonist acting at the glycine site. Potent competitive inhibitor of L-glutamate transport into synaptic vesicles. Also available as part of the NMDA Receptor - Glycine Site Tocriset™ .
Color: tan
Safety Data
Hazard Symbols Xi: Irritant