| Identification | |
| Name: | Hydrazine,(2-phenylethyl)- |
| Synonyms: | Hydrazine,phenethyl- (6CI,8CI); 1-(2-Phenethyl)hydrazine; 1-(2-Phenylethyl)hydrazine;1-Hydrazino-2-phenylethane; 2-Phenylethylhydrazine; Phenalzine; Phenelzine;Phenethylhydrazine; Phenylethylhydrazine; W 1544; b-Phenylethylhydrazine |
| CAS: | 51-71-8 |
| EINECS: | 200-117-9 |
| Molecular Formula: | C8H12 N2 |
| Molecular Weight: | 136.22 |
| InChI: | InChI=1/C8H12N2/c9-10-7-6-8-4-2-1-3-5-8/h1-5,10H,6-7,9H2 |
| Molecular Structure: |  |
| Properties | |
| Density: | 1.01 g/cm3 |
| Specification: |
2-Phenylethylhydrazine (CAS NO.51-71-8) is an irreversible and nonselective and monoamine oxidase inhibitor (MAOI) of the hydrazine chemical class which is used as an antidepressant and anxiolytic. Along with tranylcypromine and isocarboxazid, phenelzine is one of the few nonselective MAOIs still in widespread clinical use. 2-Phenylethylhydrazine and the other MAOIs are typically considered to be significantly more effective against clinical depression in comparison to more mainstream antidepressants like the selective serotonin reuptake inhibitors (SSRIs), but are usually reserved only as a last resort due to their prominent side effects and potentially hazardous food and drug interactions. Notably, phenelzine has shown unique efficacy in treating anxiety disorders, likely due to its actions on GABA concentrations. |
| Safety Data | |
| Hazard Symbols |
Xi: Irritant
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