| Identification | |
| Name: | Metoprolol tartrate |
| Synonyms: | Metoprolol-(+,-) (+)-tartrate salt;2-Propanol,1-[4-(2-methoxyethyl)phenoxy]-3- [(1-methylethyl)amino]-,(2R,3R)-2,3- dihydroxybutanedioate (2:1) (salt);Betaloc;Beloc;Seloken;Lopressor;Metoprolol tartrate (JAN/USP);Lopresor;(2R,3R)-2,3-dihydroxybutanedioic acid; 1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol;Prestwick_1009;2,3-dihydroxybutanedioic acid; 1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol;Lopressor (TN);Metoprolol tartaric acid; |
| CAS: | 56392-17-7 |
| EINECS: | 260-148-9 |
| Molecular Formula: | 2(C15H25NO3).(C4H6O6) |
| Molecular Weight: | 684.81464 |
| InChI: | InChI=1S/2C15H25NO3.C4H6O6/c2*1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3;5-1(3(7)8)2(6)4(9)10/h2*4-7,12,14,16-17H,8-11H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)/t;;1-,2-/m..1/s1 |
| Molecular Structure: | ![(2(C15H25NO3).(C4H6O6)) Metoprolol-(+,-) (+)-tartrate salt;2-Propanol,1-[4-(2-methoxyethyl)phenoxy]-3- [(1-methylethyl)amino...](https://img.guidechem.com/casimg/56392-17-7.gif) |
| Properties | |
| Melting Point: | 120 C |
| Density: | g/cm3 |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| Water Solubility: | H2O: 50 mg/mL |
| Solubility: | H2O: 50 mg/mL |
| Appearance: | white to off-white / powder |
| Specification: | Crystalline Powder usageEng:A ? selective aryloxypropanolamine andrenergic antagonist. Used in the treatment of a variety of cardiovascular disorder. Antihypertensive; antianginal; antiarrhythmic (class II) |
| Biological Activity: | Selective β 1 -adrenoceptor antagonist (K i values are 47, 2960 and 10100 nM for β 1 , β 2 and β 3 adrenoceptors respectively). Inhibits spontaneous endothelin-1 production in vitro and displays antihypertensive and antianginal activity in vivo . |
| Storage Temperature: | Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage. |
| Usage: | A ? selective aryloxypropanolamine andrenergic antagonist. Used in the treatment of a variety of cardiovascular disorder. Antihypertensive; antianginal; antiarrhythmic (class II) |
| Safety Data | |
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