| Identification | |
| Name: | Cyclophosphamide monohydrate |
| Synonyms: | 2H-1,3,2-Oxazaphosphorin-2-amine,N,N-bis(2-chloroethyl)tetrahydro-, 2-oxide, monohydrate (9CI);2H-1,3,2-Oxazaphosphorine, 2-[bis(2-chloroethyl)amino]tetrahydro-, 2-oxide,monohydrate (8CI);2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxidemonohydrate;Endoxanmonohydrate;2H-1,3,2-Oxazaphosphorin-2-amine,N,N-bis(2-chloroethyl)tetrahydro-, 2-oxide, hydrate (1:1); |
| CAS: | 6055-19-2 |
| EINECS: | 200-015-4 |
| Molecular Formula: | C7H15Cl2N2O2P |
| Molecular Weight: | 279.13 |
| InChI: | InChI=1/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2/t14-;/m1./s1 |
| Molecular Structure: |  |
| Properties | |
| Transport: | UN 3464 6 |
| Stability: | No data. |
| Water Solubility: | 40 G/L |
| Solubility: | H2O: 0.1 g/mL, clear, colorless |
| Appearance: | White to Off-White Solid |
| Specification: |
Cyclophosphamide hydrate (CAS NO.6055-19-2), its Synonyms are (+-)-2-(Bis(2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide monohydrate ; (Bis(chloro-2-ethyl)amino)-2-tetrahydro-3,4,5,6-oxazaphosphorine-1,3,2-oxide-2 monohydrate ; 1-Bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridine monohydrate ; 2-(Bis(2-chloroethyl)amino)-1-oxa-3-aza-2-phosphocyclohexane 2-oxide monohydrate ; 2-(Bis(2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide monohydrate ; 2-(Di(2-chloroethyl)amino)-1-oxa-3-aza-2-phosphacyclohexane-2-oxide monohydrate ; 2H-1,3,2-Oxazaphosphorin-2-amine, N,N-bis(2-chloroethyl)tetrahydro-, 2-oxide, monohydrate, (+-) ; Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester monohydrate ; Cyclophosphamide . |
| Packinggroup: | II |
| Color: | LIQUEFIES ON LOSS OF ITS WATER OF CRYSTALLIZATION Crystalline solid |
| Usage: | It is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity. Th |
| Safety Data | |
| Hazard Symbols |
T: Toxic
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