| Identification | |
| Name: | 3-Isoquinolinecarboxylicacid,2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-,hydrochloride (1:1), (3S)- |
| Synonyms: | (3S)-2-((2S)-N-((1S)-1-Carboxy-3-phenylpropyl)alanyl)-1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic acid, 2-ethyl ester, monohydrochloride;Moexipril HCl;UNII-Q1UMG3UH45;RS 10085-197;SPM 925;Univasc;CI 925; |
| CAS: | 82586-52-5 |
| Molecular Formula: | C27H34N2O7.ClH |
| Molecular Weight: | 535.029 |
| InChI: | InChI=1S/C27H34N2O7.ClH/c1-5-36-27(33)21(12-11-18-9-7-6-8-10-18)28-17(2)25(30)29-16-20-15-24(35-4)23(34-3)14-19(20)13-22(29)26(31)32;/h6-10,14-15,17,21-22,28H,5,11-13,16H2,1-4H3,(H,31,32);1H/t17-,21-,22-;/m0./s1 |
| Molecular Structure: |  |
| Properties | |
| Transport: | UN 3077 |
| Melting Point: | 141-1610C |
| Water Solubility: | soluble in water |
| Solubility: | soluble in water |
| Appearance: | a fine white to off-white powder |
| Specification: |
?Moexipril Hydrochloride (CAS NO.82586-52-5) is a crystalline solid. |
| Biological Activity: | Angiotensin-converting enzyme (ACE) inhibitor that is hydrolyzed in the liver to the active metabolite moexiprilat (IC 50 values are 2.1 and 2700 nM for moexiprilat and moexipril respectively). Antihypertensive; decreases mean blood pressure in the spontaneous hypertensive rat (SHR). Also blocks degradation of bradykinin into inactive metabolites. |
| Usage: | Moexipril Hydrochloride (CAS NO.82586-52-5) is used as Angiotensin converting enzyme (ACE) inhibitor; dimethoxy analog of quinapril. |
| Safety Data | |
| Hazard Symbols |
N:Dangerous for the environment
|
 |
|
