| Identification | |
| Name: | Nafamostat mesylate |
| Synonyms: | Benzoic acid, 4-((aminoiminomethyl)amino)-, 6-(aminoiminomethyl)-2-naphthalenyl ester, dimethanesulfonate;Ronastat;Nafamostat mesylate (USAN);Nafamostat dimethanesulfonate;Nafamostat mesilate;Benzoic acid,4-[(aminoiminomethyl)amino]-,6- (aminoiminomethyl)-2-naphthalenyl ester,dimethanesulfonate;FUT 175;Futhan;[N-[4-[6-(azaniumylcarbonimidoyl)naphthalen-2-yl]oxycarbonylphenyl]carbamimidoyl]azanium; methanesulfonate;Nafamostat mesilate (JAN);Nafamostat mesylate [USAN];Ronastat (TN);Nafamostat Mesilate(CAS No: 82956-11-4);6-Amidino-2-naphthyl 4-guanidinobenzoate dimethanesulfonate; |
| CAS: | 82956-11-4 |
| Molecular Formula: | C21H25N5O8S2 |
| Molecular Weight: | 539.63 |
| InChI: | InChI=1/C19H17N5O2.CH4O3S/c20-17(21)14-2-1-13-10-16(8-5-12(13)9-14)26-18(25)11-3-6-15(7-4-11)24-19(22)23;1-5(2,3)4/h1-10H,(H3,20,21)(H4,22,23,24);1H3,(H,2,3,4) |
| Molecular Structure: |  |
| Properties | |
| Melting Point: | 259-261 ºC |
| Flash Point: | 339.1ºC |
| Boiling Point: | 637.2ºCat 760 mmHg |
| Appearance: | Tan to pale orange solid |
| Biological Activity: | Broad spectrum serine protease inhibitor. Displays selectivity for human tryptase when used at relatively low concentrations. Reduces eosinophil infiltration, mast cell activation and airway responsiveness in a murine model of asthma. |
| Flash Point: | 339.1ºC |
| Storage Temperature: | Room temp |
| Usage: |
6-Amidino-2-naphthyl 4-guanidinobenzoate dimethanesulfonate (CAS NO.82956-11-4) is used as a non-peptide proteaseinhibitor. |
| Safety Data | |
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