| Identification | |
| Name: | Sodium risedronate |
| Synonyms: | Risedronic acid [INN];Acidum risedronicum [INN-Latin];Acido risedronico [INN-Spanish];(1-Hydroxy-2-(3-pyridyl)ethylidene)diphosphonic acid;Actonel;NE-58095;RischorriteRisedronate sodium;Actonel (TN);Acide risedronique [INN-French];Risedronate sodium (USAN);Monosodium (1-hydroxy-2-(3-pyridinyl)ethylidene)bisphosphonate;Phosphonic acid, (1-hydroxy-2-(3-pyridinyl)ethylidene)bis-;Phosphonic acid,[1-hydroxy-2-(3-pyridinyl)- ethylidene]bis-,monosodium salt;Residronate sodium;RisedronateSodium;Risedronate Sodium;NE 58095; |
| CAS: | 115436-72-1 |
| Molecular Formula: | C7H10NNaO7P2 |
| Molecular Weight: | 305.094092 |
| InChI: | InChI=1S/C7H11NO7P2.Na/c9-7(16(10,11)12,17(13,14)15)4-6-2-1-3-8-5-6;/h1-3,5,9H,4H2,(H2,10,11,12)(H2,13,14,15);/q;+1/p-1 |
| Molecular Structure: | ![(C7H10NNaO7P2) Risedronic acid [INN];Acidum risedronicum [INN-Latin];Acido risedronico [INN-Spanish];(1-Hydroxy-2-(...](https://img.guidechem.com/casimg/115436-72-1.gif) |
| Properties | |
| Water Solubility: | Soluble (insoluble in alcohols, organic solvents) |
| Solubility: | Soluble (insoluble in alcohols, organic solvents) |
| Appearance: | Fine White to Off-White Crystalline Powder |
| Specification: |
?Synonyms of Sodium risedronate (CAS NO.115436-72-1) are Risedronate sodium [USAN] ; Actonel ; Monosodium (1-hydroxy-2-(3-pyridinyl)ethylidene)bisphosphonate ; NE 58095 ; Risedronate sodium ; Sodium trihydrogen (1-hydroxy-2-(3-pyridyl)ethylidene)diphosphonate ; UNII-OFG5EXG60L ; Phosphonic acid, (1-hydroxy-2-(3-pyridinyl)ethylidene)bis-, monosodium salt . |
| Biological Activity: | Orally active biphosphonate that inhibits farnesyl diphosphate (FPP) synthase. Exhibits antiproliferative and proapoptotic activity in numerous tumor cell lines and inhibits osteoclast-mediated bone reabsorption in vivo . |
| Usage: | A pyridinyl biphosphonate bone resorption inhibitor. |
| Safety Data | |
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